CCL3/Macrophage Inflammatory Protein-1α Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFNγ-Enriched Inflammatory Milieu in Trypanosoma cruzi-Induced Chronic Cardiomyopathy.

CCL3/Macrophage Inflammatory Protein-1α Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFNγ-Enriched Inflammatory Milieu in Trypanosoma cruzi-Induced Chronic Cardiomyopathy.

CCL3, member of the CC-chemokine family, has been linked to heart tissue macrophage recruitment and parasite control in mouse acute infection with Trypanosoma cruzi, the causative agent of Chagas disease. Here, we approached CCL3 participation in chronic chagasic cardiomyopathy (CCC), the main clinical forms of Chagas disease. We CCC induced in C57BL / 6 (CCL + / +) and CCL3-deficiency (CCL – / -) mice by infection with Colombia Type I strain. In CCL + / + mice, high levels CCL3 mRNA and protein were detected in heart tissue during acute and chronic infections. Survival is not affected by the shortage CCL3. Compared with CCL + / +, chronically infected CCL – / – mice presented decreased cardiac parasitism and inflammation caused by CD8 + cells and macrophages. Leukocytosis decreased in infected CCL – / – mice, in line with the accumulation of CD8 + T cells with no CCR5 + activated LFA-1 + cells in the spleen.

Furthermore, T. cruzi-infected CCL – / – mice served to reduce the frequency of interferon-gamma (IFN) + cells and the number of cell-specific IFN-producing parasite, while the cytotoxic activity of T. cruzi-specific antigen increases. CCL3-deficient macrophages stimulation with IFN improve control of parasites in the environment by reducing nitrous oxides (NOx) and tumor necrosis factor (TNF), but similar to interleukin-10 (IL-10), concentration. Compared to chronic T. cruzi-infected CCL + / + counterparts, CCL – / – mice did not show an enlarged heart, the loss of left ventricular ejection fraction, QTc prolongation and increased activity of CK-MB. Compared with CCL + / +, CCL infected – / – mice showed a decrease in the concentration of TNF, while IL-10 levels were not affected, in the heart of the neighborhood. In the spleen of CCL + / + control NI, most of CD8 + T-cells expressing CCR1 or CCR5 receptor CCL3 that IL-10 +, whereas in infected mice these cells mainly TNF +.

Lastly, blockage selective CCR1 / CCR5 (therapy Met-RANTES) in chronically infected CCL + / + mice reversed electrical abnormalities important (bradycardia, prolonged PR and QTc interval), in correlation with reduced TNF and, especially, the level of CCL3 in liver tissue , Therefore, in T. cruzi infection chronic CCL3 take part in the parasite persistence and contribute to shaping the CD8 + T-cell and macrophage inflammatory enriched heart. Furthermore, increased levels of CCL3 create scenarios with abundant IFN and TNF, is associated with cardiomyocyte injury, cardiac dysfunction and QTc prolongation, a biomarker of the severity of heart disease Chagas’.

CCL3/Macrophage Inflammatory Protein-1α Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFNγ-Enriched Inflammatory Milieu in Trypanosoma cruzi-Induced Chronic Cardiomyopathy.
CCL3/Macrophage Inflammatory Protein-1α Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFNγ-Enriched Inflammatory Milieu in Trypanosoma cruzi-Induced Chronic Cardiomyopathy.

High-fat GAIT element-mediated translational silencing of diet-induced mRNA that encodes the macrophage inflammatory proteins protect against atherosclerosis.

Previously, we identified the control mechanisms of inflammation directed by ribosomal protein L13a and “GAIT” (Gamma Active Inhibitor of Translation) elements in the mRNA targets and demonstrated that elimination in the myeloid cell-specific L13a KO mice (L13a KO) increases susceptibility to atherosclerosis and severity , Here, we investigate the mechanistic basis of this endogenous defense against atherosclerosis. We compared the molecular and cellular aspects of atherosclerosis in high fat diet (HFD) -fed L13a KO and intact (control) mice. HFD treatment induced rat control L13a release of the 60S ribosome, the formation of RNA-binding complex and further GAIT element-mediated translational silencing. atherosclerotic plaque from HFD-treated KO mice showed infiltration of inflammatory types of M1 macrophages increased.

Macrophage Inflammatory protein-1 beta (CCL4) Protein

20-abx261562
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  • 2 µg

Macrophage Inflammatory protein-1 beta (CCL4) Protein

20-abx261577
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Macrophage Inflammatory protein-1 beta (CCL4) Protein

abx261530-100g 100 µg
EUR 3550

Macrophage Inflammatory protein-1 beta (CCL4) Protein

abx261530-10g 10 µg
EUR 325

Macrophage Inflammatory protein-1 beta (CCL4) Protein

abx261530-2g 2 µg
EUR 225

Macrophage Inflammatory protein-1 beta (CCL4) Protein

abx261562-100g 100 µg
EUR 3550

Macrophage Inflammatory protein-1 beta (CCL4) Protein

abx261562-10g 10 µg
EUR 325

Macrophage Inflammatory protein-1 beta (CCL4) Protein

abx261577-100g 100 µg
EUR 3550

Macrophage Inflammatory protein-1 beta (CCL4) Protein

abx261577-10g 10 µg
EUR 325

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx313218
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx129308
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx129984
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx173422
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  • 200 ug

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx173423
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  • 200 ug

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx173424
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  • 200 ug

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx173425
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  • 1 mg
  • 200 ug

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx177421
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx177422
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx177423
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx128491
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx117137-100ug 100 ug
EUR 560.4

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx104064
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx104065
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx104066
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx104067
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

20-abx001404
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx025005-400ul 400 ul
EUR 627.6

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx025005-80l 80 µl
EUR 343.2

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx001404-100l 100 µl
EUR 400

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx001404-20l 20 µl
EUR 175

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx001404-50l 50 µl
EUR 275

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx128491-100l 100 µl
EUR 250

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx128491-1ml 1 ml
EUR 675

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx128491-200l 200 µl
EUR 312.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx129984-100l 100 µl
EUR 262.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx129984-1ml 1 ml
EUR 725

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx129984-200l 200 µl
EUR 337.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx129308-100l 100 µl
EUR 300

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx129308-1ml 1 ml
EUR 875

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx129308-200l 200 µl
EUR 375

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx104064-100g 100 µg
EUR 475

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx104064-20g 20 µg
EUR 212.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx104064-50g 50 µg
EUR 250

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx104065-100g 100 µg
EUR 725

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx104065-20g 20 µg
EUR 262.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx104065-50g 50 µg
EUR 337.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx104066-100g 100 µg
EUR 775

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx104066-20g 20 µg
EUR 275

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx104066-50g 50 µg
EUR 350

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx104067-100g 100 µg
EUR 812.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx104067-20g 20 µg
EUR 287.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx104067-50g 50 µg
EUR 362.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx117137-100g 100 µg
EUR 450

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx025005-400l 400 µl
EUR 518.75

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx173422-100l 100 µl
EUR 712.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx173422-1ml 1 ml Ask for price

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx173422-200l 200 µl Ask for price

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx173424-100l 100 µl
EUR 775

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx173424-1ml 1 ml Ask for price

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx173424-200l 200 µl Ask for price

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx173425-100l 100 µl
EUR 775

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx173425-1ml 1 ml Ask for price

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx173425-200l 200 µl Ask for price

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx375301-96tests 96 tests
EUR 337.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx313218-100g 100 µg
EUR 362.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx313218-20g 20 µg
EUR 162.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx313218-50g 50 µg
EUR 250

Active Macrophage Inflammatory Protein 1 Beta (MIP1b)

APA093Hu02 10ug
EUR 270

Active Macrophage Inflammatory Protein 1 Beta (MIP1b)

APA093Hu61 10ug
EUR 220

Active Macrophage Inflammatory Protein 1 Beta (MIP1b)

APA093Hu62 10ug
EUR 300

Active Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU59096-100ug 100ug
EUR 996.7

Active Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU59096-1mg 1mg
EUR 3896.1

Active Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU59096-50ug 50ug
EUR 622.7

Active Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU56329-100ug 100ug
EUR 833.8

Active Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU56329-1mg 1mg
EUR 3690.7

Active Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU56329-50ug 50ug
EUR 649

Rat Macrophage Inflammatory Protein 1 Beta ELISA Kit

IRTMIP1BKT each
EUR 718
Description: Rat Macrophage Inflammatory Protein 1 Beta ELISA Kit

Pig Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein

20-abx654244
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Cow Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein

20-abx067890
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Dog Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein

20-abx067891
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Rat Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein

20-abx067893
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Rat Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein

20-abx167917
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Dog Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein

abx067891-50ml 50 ml
EUR 437.5

Pig Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein

abx654244-10g 10 µg
EUR 5300

Pig Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein

abx654244-2g 2 µg
EUR 2112.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (HRP)

20-abx313219
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (HRP)

abx313219-100g 100 µg
EUR 362.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (HRP)

abx313219-20g 20 µg
EUR 162.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (HRP)

abx313219-50g 50 µg
EUR 250

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (FITC)

20-abx271109
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (FITC)

20-abx271111
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (FITC)

20-abx313220
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Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (FITC)

abx271109-1ml 1 ml
EUR 1137.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (FITC)

abx271109-200l 200 µl
EUR 462.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (FITC)

abx271111-1ml 1 ml
EUR 1075

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (FITC)

abx271111-200l 200 µl
EUR 437.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (FITC)

abx313220-100g 100 µg
EUR 362.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (FITC)

abx313220-20g 20 µg
EUR 162.5

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody (FITC)

abx313220-50g 50 µg
EUR 250

Eukaryotic Macrophage Inflammatory Protein 1 Beta (MIP1b)

EPA093Hu61 10ug
EUR 220

Eukaryotic Macrophage Inflammatory Protein 1 Beta (MIP1b)

EPA093Hu62 10ug
EUR 240

Eukaryotic Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU58937-100ug 100ug
EUR 871.2

Eukaryotic Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU58937-1mg 1mg
EUR 3432

Eukaryotic Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU58937-50ug 50ug
EUR 544.5

Eukaryotic Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU59023-100ug 100ug
EUR 950.4

Eukaryotic Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU59023-1mg 1mg
EUR 3744

Eukaryotic Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU59023-50ug 50ug
EUR 594

Mouse Macrophage Inflammatory Protein 1 Beta ELISA Kit

IMSMIP1BKT each
EUR 483
Description: Mouse Macrophage Inflammatory Protein 1 Beta ELISA Kit

Human Macrophage Inflammatory Protein 1 Beta ELISA Kit

IHUMIP1BKT each
EUR 667
Description: Human Macrophage Inflammatory Protein 1 Beta ELISA Kit

Mouse Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein

20-abx067892
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Human Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein

20-abx167918
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Human Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein

abx167918-1ml 1 ml
EUR 200

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU51049-100ug 100ug
EUR 455.4

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU51049-1mg 1mg
EUR 2020.2

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU51049-50ug 50ug
EUR 366.3

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU42641-100ug 100ug
EUR 578.6

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU42641-1mg 1mg
EUR 2566.2

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU42641-50ug 50ug
EUR 465.3

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU42642-100ug 100ug
EUR 603.9

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU42642-1mg 1mg
EUR 2675.4

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU42642-50ug 50ug
EUR 485.1

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU42643-100ug 100ug
EUR 566.5

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU42643-1mg 1mg
EUR 2511.6

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU42643-50ug 50ug
EUR 455.4

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU42644-100ug 100ug
EUR 591.8

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU42644-1mg 1mg
EUR 2620.8

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU42644-50ug 50ug
EUR 475.2

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU57857-100ug 100ug
EUR 510.8

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU57857-1mg 1mg
EUR 2371.2

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU57857-50ug 50ug
EUR 418

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU57948-100ug 100ug
EUR 535.1

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU57948-1mg 1mg
EUR 2483.5

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU57948-50ug 50ug
EUR 415.9

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU51347-100ug 100ug
EUR 480.7

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU51347-1mg 1mg
EUR 2129.4

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU51347-50ug 50ug
EUR 386.1

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU54587-100ug 100ug
EUR 616

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU54587-1mg 1mg
EUR 2730

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPU54587-50ug 50ug
EUR 495

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPA093Bo01 10ug
EUR 188

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

4-RPA093Bo01
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  • 5 mg
Description: Recombinant Bovine Macrophage Inflammatory Protein 1 Beta expressed in: E.coli

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPA093Ca01 10ug
EUR 196

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

4-RPA093Ca01
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  • 100 ug
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  • 5 mg
Description: Recombinant Dog Macrophage Inflammatory Protein 1 Beta expressed in: E.coli

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPA093Hu01 10ug
EUR 148

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

4-RPA093Hu01
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  • 100 ug
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  • 1 mg
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  • 50ug
  • 5 mg
Description: Recombinant Human Macrophage Inflammatory Protein 1 Beta expressed in: E.coli

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPA093Hu02 10ug
EUR 152

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPA093Mu01 10ug
EUR 184

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

4-RPA093Mu01
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  • 100 ug
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  • 50ug
  • 5 mg
Description: Recombinant Mouse Macrophage Inflammatory Protein 1 Beta expressed in: E.coli

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPA093Ra01 10ug
EUR 192

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

4-RPA093Ra01
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Description: Recombinant Rat Macrophage Inflammatory Protein 1 Beta expressed in: E.coli

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPA093Rb01 10ug
EUR 200

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

4-RPA093Rb01
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Description: Recombinant Rabbit Macrophage Inflammatory Protein 1 Beta expressed in: E.coli

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

RPA093Si01 10ug
EUR 156

Recombinant Macrophage Inflammatory Protein 1 Beta (MIP1b)

4-RPA093Si01
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Description: Recombinant Simian Macrophage Inflammatory Protein 1 Beta expressed in: E.coli

Human Macrophage Inflammatory Protein 3 beta Antibody

32986-05111 150 ug
EUR 215

Macrophage Inflammatory Protein 3 Beta (MIP3b) Antibody

20-abx129816
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  • 100 ug
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Macrophage Inflammatory Protein 3 Beta (MIP3b) Antibody

20-abx173427
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  • 200 ug

Macrophage Inflammatory Protein 3 Beta (MIP3b) Antibody

20-abx173428
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Macrophage Inflammatory Protein 3 Beta (MIP3b) Antibody

20-abx173429
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  • 1 mg
  • 200 ug

Macrophage Inflammatory Protein 3 Beta (MIP3b) Antibody

20-abx177428
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  • 100 ug
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Macrophage Inflammatory Protein 3 Beta (MIP3b) Antibody

20-abx177429
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  • 1 mg
  • 200 ug

Macrophage Inflammatory Protein 3 Beta (MIP3b) Antibody

20-abx177430
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  • 1 mg
  • 200 ug

Macrophage Inflammatory Protein 3 Beta (MIP3b) Antibody

20-abx104893
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Macrophage Inflammatory Protein 3 Beta (MIP3b) Antibody

20-abx104068
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Macrophage Inflammatory Protein 3 Beta (MIP3b) Antibody

20-abx104069
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Macrophages from knockout mice showed increased phagocytic activity and elevated LDL receptor expression and pro-inflammatory mediators. NanoString analysis of plaque from KO mice showed upregulation of mRNA that encodes a number of inflammatory proteins. bioinformatics analysis showed potential GAIT elements in 3’UTRs some of this mRNA.

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