Our study aims to screen and explore the expression of inflammatory factors in patients with keloid and to investigate how hyperbaric oxygen (HBO) therapy affects the level of expression of interleukin-12p40 (IL-12p40), macrophage inflammatory protein-1β (MIP- 1β), factor growth-BB (PDGF-BB), and interleukin-1 receptor antagonist (IL-1Ra) 30 patients were randomly divided into 3 groups platelet-derived following :. keloid keloid samples from patients treated with HBO therapy (A), keloid samples of keloid patients treated without HBO therapy (B), and normal control skin samples derived from individuals who do not have a clear scar tissue (C).
Each group included 10 samples. inflammatory factors in keloid tissue measured by MILLIPLEX multiplexed Luminex system. Hematoxylin and eosin, immunohistochemical staining and Western blotting was used to observe the morphological differences in different tissues and expression levels. The level of expression of inflammatory mediators, including IL-12p40, MIP-1β, PDGF -BB, and IL-1Ra, the keloid tissue were significantly different from those in normal skin samples. Hematoxylin and eosin showed inflammatory infiltration significantly greater in keloid tissue.
Significantly different expression levels observed in groups A, B, and C. significantly altered levels of inflammatory factors in the samples of keloid patients were observed, indicating that the formation of keloids potentially associated with the inflammatory response. HBO therapy can significantly affect expression levels of IL-12p40, MIP-1β, PDGF-BB, and IL-1Ra, suggesting that the effects of HBO therapy is associated with attenuation of the inflammatory response.

Giardia lamblia p65RelA Reducing NF-kB proteins and modulate the level of LPS-induced pro-inflammatory response in macrophages.
Protozoan Giardia lamblia is the most common cause of gastrointestinal parasitic infections worldwide. parasites developed sophisticated, yet not fully disclosed, mechanisms to escape the immune system and the growth in the intestine. To better understand the interaction of G. lamblia by host immune cells, we examined the ability of the parasite to modulate canonical activation of mouse macrophages (Raw 264.7 cell line) and human monocyte-derived macrophages induced by TLR4 agonist, lipopolysaccharide (LPS). We observed that LPS-destructive G.
Anti-Macrophage Inflammatory Protein 3 beta/Ccl19 Antibody |
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A01605-1 | BosterBio | 100ug/vial | EUR 294 |
Macrophage Inflammatory protein-1 alpha (CCL3) Protein |
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20-abx261543 | Abbexa |
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Macrophage Inflammatory protein-1 alpha (CCL3) Protein |
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20-abx261593 | Abbexa |
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Macrophage Inflammatory protein-1 alpha (CCL3) Protein |
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20-abx261779 | Abbexa |
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Macrophage Inflammatory protein-1 alpha (CCL3) Protein |
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20-abx262048 | Abbexa |
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Macrophage Inflammatory protein-1 alpha (CCL3) Protein |
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20-abx262942 | Abbexa |
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Anti-Macrophage Inflammatory Protein 1 (4E7) |
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YF-MA10821 | Abfrontier | 100 ug | EUR 363 |
Description: Mouse monoclonal to Macrophage Inflammatory Protein 1 |
anti-Macrophage Inflammatory Protein 1 beta |
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YF-PA24669 | Abfrontier | 50 ul | EUR 334 |
Description: Mouse polyclonal to Macrophage Inflammatory Protein 1 beta |
anti-Macrophage Inflammatory Protein 1 beta |
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YF-PA14543 | Abfrontier | 100 ug | EUR 403 |
Description: Rabbit polyclonal to Macrophage Inflammatory Protein 1 beta |
Recombinant (E.Coli) Human Macrophage Inflammatory protein-1 alpha (CCL3), His-tag |
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RP-1048 | Alpha Diagnostics | 10 ug | EUR 286 |
Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody |
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20-abx132198 | Abbexa |
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Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody |
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20-abx130147 | Abbexa |
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Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody |
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20-abx130793 | Abbexa |
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Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody |
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20-abx128490 | Abbexa |
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Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody |
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20-abx104126 | Abbexa |
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Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody |
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20-abx104127 | Abbexa |
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Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody |
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20-abx006015 | Abbexa |
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Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody |
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abx411717-01mg | Abbexa | 0.1 mg | EUR 704 |
Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody |
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abx411758-01mg | Abbexa | 0.1 mg | EUR 704 |
Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody |
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abx412413-01mg | Abbexa | 0.1 mg | EUR 676 |
Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody |
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abx412553-01mg | Abbexa | 0.1 mg | EUR 704 |
Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody |
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20-abx322950 | Abbexa |
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Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody |
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20-abx177417 | Abbexa |
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Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody |
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20-abx177418 | Abbexa |
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Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody |
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20-abx177419 | Abbexa |
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Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody |
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20-abx177420 | Abbexa |
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Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody |
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20-abx173420 | Abbexa |
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Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody |
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20-abx173421 | Abbexa |
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Eukaryotic Macrophage Inflammatory Protein 1 Alpha (MIP1a) |
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4-EPA092Hu51 | Cloud-Clone |
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Description: Recombinant Human Macrophage Inflammatory Protein 1 Alpha expressed in: Yeast |
Eukaryotic Macrophage Inflammatory Protein 1 Alpha (MIP1a) |
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4-EPA092Hu61 | Cloud-Clone |
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Description: Recombinant Human Macrophage Inflammatory Protein 1 Alpha expressed in: 293F cell |
Active Macrophage Inflammatory Protein 1 Alpha (MIP1a) |
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4-APA092Hu61 | Cloud-Clone |
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Description: Recombinant Human Macrophage Inflammatory Protein 1 Alpha expressed in: 293F cell |
Recombinant Macrophage Inflammatory Protein 1 Alpha (MIP1a) |
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4-RPA092Ca01 | Cloud-Clone |
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Description: Recombinant Dog Macrophage Inflammatory Protein 1 Alpha expressed in: E.coli |
Recombinant Macrophage Inflammatory Protein 1 Alpha (MIP1a) |
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4-RPA092Hu01 | Cloud-Clone |
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Description: Recombinant Human Macrophage Inflammatory Protein 1 Alpha expressed in: E.coli |
Recombinant Macrophage Inflammatory Protein 1 Alpha (MIP1a) |
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4-RPA092Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Macrophage Inflammatory Protein 1 Alpha expressed in: E.coli |
Recombinant Macrophage Inflammatory Protein 1 Alpha (MIP1a) |
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4-RPA092Ra01 | Cloud-Clone |
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Description: Recombinant Rat Macrophage Inflammatory Protein 1 Alpha expressed in: E.coli |
Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody |
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abx117137-100ug | Abbexa | 100 ug | EUR 467 |
MIP-1a Macrophage Inflammatory Protein-1 Alpha Human Recombinant Protein (CCL3), His Tag |
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PROTP10147-1 | BosterBio | Regular: 10ug | EUR 317 |
Description: Macrophage Inflammatory Protein-1 alpha His Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 68 amino acids and having a molecular mass of 7820 Dalton with an amino-terminal hexahistidine tag. ;The MIP-1a-His is purified by proprietary chromatographic techniques. |
MIP-3a Macrophage Inflammatory Protein-3 alpha Human Recombinant Protein (CCL20) |
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PROTP78556-1 | BosterBio | Regular: 20ug | EUR 317 |
Description: MIP-3 Alpha Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 8 kDa. ;The MIP-3a is purified by proprietary chromatographic techniques. |
anti-Macrophage inflammatory protein 5 |
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YF-PA24672 | Abfrontier | 50 ul | EUR 334 |
Description: Mouse polyclonal to Macrophage inflammatory protein 5 |
anti-Macrophage Inflammatory Protein 4 |
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YF-PA24674 | Abfrontier | 50 ul | EUR 334 |
Description: Mouse polyclonal to Macrophage Inflammatory Protein 4 |
anti-Macrophage inflammatory protein 5 |
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YF-PA14551 | Abfrontier | 100 ul | EUR 403 |
Description: Rabbit polyclonal to Macrophage inflammatory protein 5 |
anti-Macrophage inflammatory protein 5 |
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YF-PA14552 | Abfrontier | 100 ug | EUR 403 |
Description: Rabbit polyclonal to Macrophage inflammatory protein 5 |
anti-Macrophage Inflammatory Protein 4 |
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YF-PA14553 | Abfrontier | 100 ul | EUR 403 |
Description: Rabbit polyclonal to Macrophage Inflammatory Protein 4 |
anti-Macrophage Inflammatory Protein 4 |
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YF-PA14554 | Abfrontier | 100 ug | EUR 403 |
Description: Rabbit polyclonal to Macrophage Inflammatory Protein 4 |
anti-Macrophage Inflammatory Protein 3 |
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YF-PA14559 | Abfrontier | 50 ug | EUR 363 |
Description: Mouse polyclonal to Macrophage Inflammatory Protein 3 |
anti-Macrophage Inflammatory Protein 3 |
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YF-PA14560 | Abfrontier | 100 ul | EUR 403 |
Description: Rabbit polyclonal to Macrophage Inflammatory Protein 3 |
anti-Macrophage Inflammatory Protein 3 |
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YF-PA14561 | Abfrontier | 100 ug | EUR 403 |
Description: Rabbit polyclonal to Macrophage Inflammatory Protein 3 |
anti-Macrophage inflammatory protein 5 |
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YF-PA20144 | Abfrontier | 50 ug | EUR 363 |
Description: Mouse polyclonal to Macrophage inflammatory protein 5 |
anti-Macrophage inflammatory protein 5 |
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YF-PA20145 | Abfrontier | 100 ul | EUR 403 |
Description: Rabbit polyclonal to Macrophage inflammatory protein 5 |
anti-Macrophage inflammatory protein 5 |
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YF-PA20146 | Abfrontier | 100 ug | EUR 403 |
Description: Rabbit polyclonal to Macrophage inflammatory protein 5 |
Dog Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein |
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20-abx069746 | Abbexa |
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Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein |
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20-abx167920 | Abbexa |
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Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein |
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20-abx166105 | Abbexa |
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Rat Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein |
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20-abx166111 | Abbexa |
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Cow Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein |
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20-abx654241 | Abbexa |
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Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein |
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20-abx651540 | Abbexa |
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Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein |
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20-abx651541 | Abbexa |
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Cow Macrophage Inflammatory Protein 1 Alpha (MIP1A) Protein |
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abx670146-5ug | Abbexa | 5 ug | EUR 411 |
Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein |
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abx670285-10ug | Abbexa | 10 ug | EUR 565 |
Macrophage Inflammatory Protein-3 alpha (CCL20) |
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PR27176 | Neuromics | 20 ug | EUR 318 |
Mouse Macrophage Inflammatory Protein- 1 Alpha, MIP- 1 Alpha ELI |
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ELA-E0092m | Lifescience Market | 96 Tests | EUR 865 |
Rat Macrophage Inflammatory Protein- 1 Alpha, MIP- 1 Alpha ELISA |
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ELA-E0092r | Lifescience Market | 96 Tests | EUR 886 |
Recombinant Human Macrophage Inflammatory protein-1 alpha (CCL3) |
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7-02008 | CHI Scientific | 5µg | Ask for price |
Recombinant Human Macrophage Inflammatory protein-1 alpha (CCL3) |
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7-02009 | CHI Scientific | 20µg | Ask for price |
Recombinant Human Macrophage Inflammatory protein-1 alpha (CCL3) |
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7-02010 | CHI Scientific | 1mg | Ask for price |
Recombinant Mouse Macrophage Inflammatory protein-1 alpha (CCL3) |
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7-02014 | CHI Scientific | 2µg | Ask for price |
Recombinant Mouse Macrophage Inflammatory protein-1 alpha (CCL3) |
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7-02015 | CHI Scientific | 10µg | Ask for price |
Recombinant Mouse Macrophage Inflammatory protein-1 alpha (CCL3) |
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7-02016 | CHI Scientific | 1mg | Ask for price |
Recombinant Rat Macrophage Inflammatory protein-1 alpha (CCL3) |
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7-02017 | CHI Scientific | 5µg | Ask for price |
Recombinant Rat Macrophage Inflammatory protein-1 alpha (CCL3) |
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7-02018 | CHI Scientific | 20µg | Ask for price |
Recombinant Rat Macrophage Inflammatory protein-1 alpha (CCL3) |
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7-02019 | CHI Scientific | 1mg | Ask for price |
Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody Pair |
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20-abx370032 | Abbexa |
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Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody (Biotin) |
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abx411759-50ug | Abbexa | 50 ug | EUR 676 |
Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody (Biotin) |
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abx412414-50ug | Abbexa | 50 ug | EUR 676 |
Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody (Biotin) |
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20-abx272654 | Abbexa |
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BSA Conjugated Macrophage Inflammatory Protein 1 Alpha (MIP1a) |
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4-CPA092Ra11 | Cloud-Clone |
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Description: Recombinant Rat Macrophage Inflammatory Protein 1 Alpha expressed in: Protein conjugation |
OVA Conjugated Macrophage Inflammatory Protein 1 Alpha (MIP1a) |
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4-CPA092Ra21 | Cloud-Clone |
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Description: Recombinant Rat Macrophage Inflammatory Protein 1 Alpha expressed in: Protein conjugation |
Macrophage Inflammatory protein-3 alpha (CCL20) Protein |
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20-abx261545 | Abbexa |
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Macrophage Inflammatory protein-3 alpha (CCL20) Protein |
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20-abx261594 | Abbexa |
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Macrophage Inflammatory protein-3 alpha (CCL20) Protein |
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20-abx262350 | Abbexa |
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Recombinant (E.Coli) Human Macrophage Inflammatory protein-1 beta (CCL4) |
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RP-1009 | Alpha Diagnostics | 10 ug | EUR 286 |
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein (Active) |
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20-abx655750 | Abbexa |
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Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein (Active) |
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20-abx651409 | Abbexa |
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Rat Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein (BSA) |
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20-abx651785 | Abbexa |
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Anti-Macrophage inflammatory protein 5 (1D7) |
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YF-MA15363 | Abfrontier | 100 ug | EUR 363 |
Description: Mouse monoclonal to Macrophage inflammatory protein 5 |
Anti-Macrophage inflammatory protein 5 (4G10) |
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YF-MA15364 | Abfrontier | 100 ug | EUR 363 |
Description: Mouse monoclonal to Macrophage inflammatory protein 5 |
Anti-Macrophage inflammatory protein 5 (3H1) |
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YF-MA15365 | Abfrontier | 100 ug | EUR 363 |
Description: Mouse monoclonal to Macrophage inflammatory protein 5 |
Anti-Macrophage inflammatory protein 5 (3B7) |
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YF-MA15366 | Abfrontier | 100 ug | EUR 363 |
Description: Mouse monoclonal to Macrophage inflammatory protein 5 |
Anti-Macrophage inflammatory protein 5 (3B1) |
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YF-MA15367 | Abfrontier | 100 ug | EUR 363 |
Description: Mouse monoclonal to Macrophage inflammatory protein 5 |
Anti-Macrophage Inflammatory Protein 4 (2C6) |
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YF-MA15369 | Abfrontier | 100 ug | EUR 363 |
Description: Mouse monoclonal to Macrophage Inflammatory Protein 4 |
Anti-Macrophage inflammatory protein 5 (3D3) |
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YF-MA19031 | Abfrontier | 100 ug | EUR 363 |
Description: Mouse monoclonal to Macrophage inflammatory protein 5 |
Macrophage Inflammatory Protein 3 Alpha (MIP3a) Antibody |
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20-abx131764 | Abbexa |
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lamblia generate pro-inflammatory status in these macrophage-like cells through inhibition of cyclooxygenase-2 and inducible nitric oxide synthase expression and NO production next. This effect is partly due to the activity of three protease G. lamblia, 135 kDa cysteine protease metalloprotease and two with 75 and 63 kDa, which divides the p65RelA subunit of nuclear factor-kappa B (NF-kB). In addition, TNF and CCl4 transcription increases with the presence of parasites. Overall, our data suggest that the G. lamblia modulated macrophage inflammatory response through a reduction in the value of NF-kB, thus silencing the critical signaling pathways of innate host immune response.
Pneumonia is the leading cause of hospitalization worldwide. In addition to viral, bacterial co-infection dramatically worsen the infection. In general, the surfactant protein A (SP-A) is the first line of immune defense. In this study, we analyzed whether influenza A virus (IAV) and / or Staphylococcus aureus (S. aureus) infection affects the expression of SP-A. To reflect the situation in the lungs, we used a model of human alveolar-on-a-chip and murine model of pneumonia.