Effects of hyperbaric oxygen therapy on the expression levels of the inflammatory factors interleukin-12p40, macrophage inflammatory protein-1β, platelet-derived growth factor-BB, and interleukin-1 receptor antagonist in keloids.

Effects of hyperbaric oxygen therapy on the expression levels of the inflammatory factors interleukin-12p40, macrophage inflammatory protein-1β, platelet-derived growth factor-BB, and interleukin-1 receptor antagonist in keloids.

Our study aims to screen and explore the expression of inflammatory factors in patients with keloid and to investigate how hyperbaric oxygen (HBO) therapy affects the level of expression of interleukin-12p40 (IL-12p40), macrophage inflammatory protein-1β (MIP- 1β), factor growth-BB (PDGF-BB), and interleukin-1 receptor antagonist (IL-1Ra) 30 patients were randomly divided into 3 groups platelet-derived following :. keloid keloid samples from patients treated with HBO therapy (A), keloid samples of keloid patients treated without HBO therapy (B), and normal control skin samples derived from individuals who do not have a clear scar tissue (C).

Each group included 10 samples. inflammatory factors in keloid tissue measured by MILLIPLEX multiplexed Luminex system. Hematoxylin and eosin, immunohistochemical staining and Western blotting was used to observe the morphological differences in different tissues and expression levels. The level of expression of inflammatory mediators, including IL-12p40, MIP-1β, PDGF -BB, and IL-1Ra, the keloid tissue were significantly different from those in normal skin samples. Hematoxylin and eosin showed inflammatory infiltration significantly greater in keloid tissue.

Significantly different expression levels observed in groups A, B, and C. significantly altered levels of inflammatory factors in the samples of keloid patients were observed, indicating that the formation of keloids potentially associated with the inflammatory response. HBO therapy can significantly affect expression levels of IL-12p40, MIP-1β, PDGF-BB, and IL-1Ra, suggesting that the effects of HBO therapy is associated with attenuation of the inflammatory response.

Effects of hyperbaric oxygen therapy on the expression levels of the inflammatory factors interleukin-12p40, macrophage inflammatory protein-1β, platelet-derived growth factor-BB, and interleukin-1 receptor antagonist in keloids.
Effects of hyperbaric oxygen therapy on the expression levels of the inflammatory factors interleukin-12p40, macrophage inflammatory protein-1β, platelet-derived growth factor-BB, and interleukin-1 receptor antagonist in keloids.

Giardia lamblia p65RelA Reducing NF-kB proteins and modulate the level of LPS-induced pro-inflammatory response in macrophages.

Protozoan Giardia lamblia is the most common cause of gastrointestinal parasitic infections worldwide. parasites developed sophisticated, yet not fully disclosed, mechanisms to escape the immune system and the growth in the intestine. To better understand the interaction of G. lamblia by host immune cells, we examined the ability of the parasite to modulate canonical activation of mouse macrophages (Raw 264.7 cell line) and human monocyte-derived macrophages induced by TLR4 agonist, lipopolysaccharide (LPS). We observed that LPS-destructive G.

Anti-Macrophage Inflammatory Protein 3 beta/Ccl19 Antibody

A01605-1 100ug/vial
EUR 294

Macrophage Inflammatory protein-1 alpha (CCL3) Protein

20-abx261543
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

Macrophage Inflammatory protein-1 alpha (CCL3) Protein

20-abx261593
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

Macrophage Inflammatory protein-1 alpha (CCL3) Protein

20-abx261779
  • EUR 328.00
  • EUR 3933.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg

Macrophage Inflammatory protein-1 alpha (CCL3) Protein

20-abx262048
  • EUR 328.00
  • EUR 4532.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg

Macrophage Inflammatory protein-1 alpha (CCL3) Protein

20-abx262942
  • EUR 328.00
  • EUR 6397.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg

Anti-Macrophage Inflammatory Protein 1 (4E7)

YF-MA10821 100 ug
EUR 363
Description: Mouse monoclonal to Macrophage Inflammatory Protein 1

anti-Macrophage Inflammatory Protein 1 beta

YF-PA24669 50 ul
EUR 334
Description: Mouse polyclonal to Macrophage Inflammatory Protein 1 beta

anti-Macrophage Inflammatory Protein 1 beta

YF-PA14543 100 ug
EUR 403
Description: Rabbit polyclonal to Macrophage Inflammatory Protein 1 beta

Recombinant (E.Coli) Human Macrophage Inflammatory protein-1 alpha (CCL3), His-tag

RP-1048 10 ug
EUR 286

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody

20-abx132198
  • EUR 314.00
  • EUR 133.00
  • EUR 815.00
  • EUR 425.00
  • EUR 272.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody

20-abx130147
  • EUR 342.00
  • EUR 133.00
  • EUR 954.00
  • EUR 481.00
  • EUR 286.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody

20-abx130793
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody

20-abx128490
  • EUR 314.00
  • EUR 133.00
  • EUR 815.00
  • EUR 425.00
  • EUR 272.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody

20-abx104126
  • EUR 300.00
  • EUR 704.00
  • EUR 356.00
  • EUR 154.00
  • EUR 244.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody

20-abx104127
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody

20-abx006015
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody

abx411717-01mg 0.1 mg
EUR 704

Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody

abx411758-01mg 0.1 mg
EUR 704

Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody

abx412413-01mg 0.1 mg
EUR 676

Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody

abx412553-01mg 0.1 mg
EUR 704

Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody

20-abx322950
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody

20-abx177417
  • EUR 314.00
  • EUR 133.00
  • EUR 815.00
  • EUR 425.00
  • EUR 272.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody

20-abx177418
  • EUR 356.00
  • EUR 133.00
  • EUR 1038.00
  • EUR 509.00
  • EUR 300.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody

20-abx177419
  • EUR 1135.00
  • EUR 551.00
  • 1 mg
  • 200 ug

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody

20-abx177420
  • EUR 1288.00
  • EUR 620.00
  • 1 mg
  • 200 ug

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody

20-abx173420
  • EUR 300.00
  • EUR 704.00
  • EUR 356.00
  • EUR 154.00
  • EUR 244.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody

20-abx173421
  • EUR 871.00
  • EUR 453.00
  • 1 mg
  • 200 ug

Eukaryotic Macrophage Inflammatory Protein 1 Alpha (MIP1a)

4-EPA092Hu51
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Macrophage Inflammatory Protein 1 Alpha expressed in: Yeast

Eukaryotic Macrophage Inflammatory Protein 1 Alpha (MIP1a)

4-EPA092Hu61
  • EUR 651.04
  • EUR 277.00
  • EUR 2166.40
  • EUR 788.80
  • EUR 1477.60
  • EUR 499.00
  • EUR 5266.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Macrophage Inflammatory Protein 1 Alpha expressed in: 293F cell

Active Macrophage Inflammatory Protein 1 Alpha (MIP1a)

4-APA092Hu61
  • EUR 740.64
  • EUR 301.00
  • EUR 2502.40
  • EUR 900.80
  • EUR 1701.60
  • EUR 559.00
  • EUR 6106.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Macrophage Inflammatory Protein 1 Alpha expressed in: 293F cell

Recombinant Macrophage Inflammatory Protein 1 Alpha (MIP1a)

4-RPA092Ca01
  • EUR 548.00
  • EUR 250.00
  • EUR 1780.00
  • EUR 660.00
  • EUR 1220.00
  • EUR 430.00
  • EUR 4300.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Dog Macrophage Inflammatory Protein 1 Alpha expressed in: E.coli

Recombinant Macrophage Inflammatory Protein 1 Alpha (MIP1a)

4-RPA092Hu01
  • EUR 467.36
  • EUR 228.00
  • EUR 1477.60
  • EUR 559.20
  • EUR 1018.40
  • EUR 376.00
  • EUR 3544.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Macrophage Inflammatory Protein 1 Alpha expressed in: E.coli

Recombinant Macrophage Inflammatory Protein 1 Alpha (MIP1a)

4-RPA092Mu01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Macrophage Inflammatory Protein 1 Alpha expressed in: E.coli

Recombinant Macrophage Inflammatory Protein 1 Alpha (MIP1a)

4-RPA092Ra01
  • EUR 528.29
  • EUR 244.00
  • EUR 1706.08
  • EUR 635.36
  • EUR 1170.72
  • EUR 416.00
  • EUR 4115.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Macrophage Inflammatory Protein 1 Alpha expressed in: E.coli

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

abx117137-100ug 100 ug
EUR 467

MIP-1a Macrophage Inflammatory Protein-1 Alpha Human Recombinant Protein (CCL3), His Tag

PROTP10147-1 Regular: 10ug
EUR 317
Description: Macrophage Inflammatory Protein-1 alpha His Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 68 amino acids and having a molecular mass of 7820 Dalton with an amino-terminal hexahistidine tag. ;The MIP-1a-His is purified by proprietary chromatographic techniques.

MIP-3a Macrophage Inflammatory Protein-3 alpha Human Recombinant Protein (CCL20)

PROTP78556-1 Regular: 20ug
EUR 317
Description: MIP-3 Alpha Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 8 kDa. ;The MIP-3a is purified by proprietary chromatographic techniques.

anti-Macrophage inflammatory protein 5

YF-PA24672 50 ul
EUR 334
Description: Mouse polyclonal to Macrophage inflammatory protein 5

anti-Macrophage Inflammatory Protein 4

YF-PA24674 50 ul
EUR 334
Description: Mouse polyclonal to Macrophage Inflammatory Protein 4

anti-Macrophage inflammatory protein 5

YF-PA14551 100 ul
EUR 403
Description: Rabbit polyclonal to Macrophage inflammatory protein 5

anti-Macrophage inflammatory protein 5

YF-PA14552 100 ug
EUR 403
Description: Rabbit polyclonal to Macrophage inflammatory protein 5

anti-Macrophage Inflammatory Protein 4

YF-PA14553 100 ul
EUR 403
Description: Rabbit polyclonal to Macrophage Inflammatory Protein 4

anti-Macrophage Inflammatory Protein 4

YF-PA14554 100 ug
EUR 403
Description: Rabbit polyclonal to Macrophage Inflammatory Protein 4

anti-Macrophage Inflammatory Protein 3

YF-PA14559 50 ug
EUR 363
Description: Mouse polyclonal to Macrophage Inflammatory Protein 3

anti-Macrophage Inflammatory Protein 3

YF-PA14560 100 ul
EUR 403
Description: Rabbit polyclonal to Macrophage Inflammatory Protein 3

anti-Macrophage Inflammatory Protein 3

YF-PA14561 100 ug
EUR 403
Description: Rabbit polyclonal to Macrophage Inflammatory Protein 3

anti-Macrophage inflammatory protein 5

YF-PA20144 50 ug
EUR 363
Description: Mouse polyclonal to Macrophage inflammatory protein 5

anti-Macrophage inflammatory protein 5

YF-PA20145 100 ul
EUR 403
Description: Rabbit polyclonal to Macrophage inflammatory protein 5

anti-Macrophage inflammatory protein 5

YF-PA20146 100 ug
EUR 403
Description: Rabbit polyclonal to Macrophage inflammatory protein 5

Dog Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein

20-abx069746
  • EUR 759.00
  • EUR 300.00
  • EUR 2388.00
  • EUR 913.00
  • EUR 537.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein

20-abx167920
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein

20-abx166105
  • EUR 690.00
  • EUR 286.00
  • EUR 2124.00
  • EUR 815.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein

20-abx166111
  • EUR 732.00
  • EUR 286.00
  • EUR 2291.00
  • EUR 871.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Cow Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein

20-abx654241
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein

20-abx651540
  • EUR 732.00
  • EUR 286.00
  • EUR 2305.00
  • EUR 885.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein

20-abx651541
  • EUR 899.00
  • EUR 328.00
  • EUR 2903.00
  • EUR 1080.00
  • EUR 620.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Cow Macrophage Inflammatory Protein 1 Alpha (MIP1A) Protein

abx670146-5ug 5 ug
EUR 411

Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein

abx670285-10ug 10 ug
EUR 565

Macrophage Inflammatory Protein-3 alpha (CCL20)

PR27176 20 ug
EUR 318

Mouse Macrophage Inflammatory Protein- 1 Alpha, MIP- 1 Alpha ELI

ELA-E0092m 96 Tests
EUR 865

Rat Macrophage Inflammatory Protein- 1 Alpha, MIP- 1 Alpha ELISA

ELA-E0092r 96 Tests
EUR 886

Recombinant Human Macrophage Inflammatory protein-1 alpha (CCL3)

7-02008 5µg Ask for price

Recombinant Human Macrophage Inflammatory protein-1 alpha (CCL3)

7-02009 20µg Ask for price

Recombinant Human Macrophage Inflammatory protein-1 alpha (CCL3)

7-02010 1mg Ask for price

Recombinant Mouse Macrophage Inflammatory protein-1 alpha (CCL3)

7-02014 2µg Ask for price

Recombinant Mouse Macrophage Inflammatory protein-1 alpha (CCL3)

7-02015 10µg Ask for price

Recombinant Mouse Macrophage Inflammatory protein-1 alpha (CCL3)

7-02016 1mg Ask for price

Recombinant Rat Macrophage Inflammatory protein-1 alpha (CCL3)

7-02017 5µg Ask for price

Recombinant Rat Macrophage Inflammatory protein-1 alpha (CCL3)

7-02018 20µg Ask for price

Recombinant Rat Macrophage Inflammatory protein-1 alpha (CCL3)

7-02019 1mg Ask for price

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody Pair

20-abx370032
  • EUR 1219.00
  • EUR 801.00
  • 10 × 96 tests
  • 5 × 96 tests

Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody (Biotin)

abx411759-50ug 50 ug
EUR 676

Macrophage Inflammatory Protein 1-Alpha (CCL3) Antibody (Biotin)

abx412414-50ug 50 ug
EUR 676

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody (Biotin)

20-abx272654
  • EUR 425.00
  • EUR 230.00
  • EUR 1219.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

BSA Conjugated Macrophage Inflammatory Protein 1 Alpha (MIP1a)

4-CPA092Ra11
  • EUR 405.54
  • EUR 211.00
  • EUR 1245.76
  • EUR 481.92
  • EUR 863.84
  • EUR 334.00
  • EUR 2964.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Macrophage Inflammatory Protein 1 Alpha expressed in: Protein conjugation

OVA Conjugated Macrophage Inflammatory Protein 1 Alpha (MIP1a)

4-CPA092Ra21
  • EUR 386.72
  • EUR 206.00
  • EUR 1175.20
  • EUR 458.40
  • EUR 816.80
  • EUR 322.00
  • EUR 2788.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Macrophage Inflammatory Protein 1 Alpha expressed in: Protein conjugation

Macrophage Inflammatory protein-3 alpha (CCL20) Protein

20-abx261545
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

Macrophage Inflammatory protein-3 alpha (CCL20) Protein

20-abx261594
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

Macrophage Inflammatory protein-3 alpha (CCL20) Protein

20-abx262350
  • EUR 328.00
  • EUR 6397.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg

Recombinant (E.Coli) Human Macrophage Inflammatory protein-1 beta (CCL4)

RP-1009 10 ug
EUR 286

Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein (Active)

20-abx655750
  • EUR 1038.00
  • EUR 356.00
  • EUR 3460.00
  • EUR 1261.00
  • EUR 718.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein (Active)

20-abx651409
  • EUR 1024.00
  • EUR 356.00
  • EUR 3349.00
  • EUR 1233.00
  • EUR 704.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Macrophage Inflammatory Protein 1 Alpha (MIP1a) Protein (BSA)

20-abx651785
  • EUR 578.00
  • EUR 258.00
  • EUR 1692.00
  • EUR 676.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Anti-Macrophage inflammatory protein 5 (1D7)

YF-MA15363 100 ug
EUR 363
Description: Mouse monoclonal to Macrophage inflammatory protein 5

Anti-Macrophage inflammatory protein 5 (4G10)

YF-MA15364 100 ug
EUR 363
Description: Mouse monoclonal to Macrophage inflammatory protein 5

Anti-Macrophage inflammatory protein 5 (3H1)

YF-MA15365 100 ug
EUR 363
Description: Mouse monoclonal to Macrophage inflammatory protein 5

Anti-Macrophage inflammatory protein 5 (3B7)

YF-MA15366 100 ug
EUR 363
Description: Mouse monoclonal to Macrophage inflammatory protein 5

Anti-Macrophage inflammatory protein 5 (3B1)

YF-MA15367 100 ug
EUR 363
Description: Mouse monoclonal to Macrophage inflammatory protein 5

Anti-Macrophage Inflammatory Protein 4 (2C6)

YF-MA15369 100 ug
EUR 363
Description: Mouse monoclonal to Macrophage Inflammatory Protein 4

Anti-Macrophage inflammatory protein 5 (3D3)

YF-MA19031 100 ug
EUR 363
Description: Mouse monoclonal to Macrophage inflammatory protein 5

Macrophage Inflammatory Protein 3 Alpha (MIP3a) Antibody

20-abx131764
  • EUR 300.00
  • EUR 704.00
  • EUR 356.00
  • EUR 154.00
  • EUR 244.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

lamblia generate pro-inflammatory status in these macrophage-like cells through inhibition of cyclooxygenase-2 and inducible nitric oxide synthase expression and NO production next. This effect is partly due to the activity of three protease G. lamblia, 135 kDa cysteine ​​protease metalloprotease and two with 75 and 63 kDa, which divides the p65RelA subunit of nuclear factor-kappa B (NF-kB). In addition, TNF and CCl4 transcription increases with the presence of parasites. Overall, our data suggest that the G. lamblia modulated macrophage inflammatory response through a reduction in the value of NF-kB, thus silencing the critical signaling pathways of innate host immune response.


Pneumonia is the leading cause of hospitalization worldwide. In addition to viral, bacterial co-infection dramatically worsen the infection. In general, the surfactant protein A (SP-A) is the first line of immune defense. In this study, we analyzed whether influenza A virus (IAV) and / or Staphylococcus aureus (S. aureus) infection affects the expression of SP-A. To reflect the situation in the lungs, we used a model of human alveolar-on-a-chip and murine model of pneumonia.

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