Effects of hyperbaric oxygen therapy on the expression levels of the inflammatory factors interleukin-12p40, macrophage inflammatory protein-1β, platelet-derived growth factor-BB, and interleukin-1 receptor antagonist in keloids.
Effects of hyperbaric oxygen therapy on the expression levels of the inflammatory factors interleukin-12p40, macrophage inflammatory protein-1β, platelet-derived growth factor-BB, and interleukin-1 receptor antagonist in keloids.
Our study aims to screen and explore the expression of inflammatory factors in patients with keloid and to investigate how hyperbaric oxygen (HBO) therapy affects the level of expression of interleukin-12p40 (IL-12p40), macrophage inflammatory protein-1β (MIP- 1β), factor growth-BB (PDGF-BB), and interleukin-1 receptor antagonist (IL-1Ra) 30 patients were randomly divided into 3 groups platelet-derived following :. keloid keloid samples from patients treated with HBO therapy (A), keloid samples of keloid patients treated without HBO therapy (B), and normal control skin samples derived from individuals who do not have a clear scar tissue (C).
Each group included 10 samples. inflammatory factors in keloid tissue measured by MILLIPLEX multiplexed Luminex system. Hematoxylin and eosin, immunohistochemical staining and Western blotting was used to observe the morphological differences in different tissues and expression levels. The level of expression of inflammatory mediators, including IL-12p40, MIP-1β, PDGF -BB, and IL-1Ra, the keloid tissue were significantly different from those in normal skin samples. Hematoxylin and eosin showed inflammatory infiltration significantly greater in keloid tissue.
Significantly different expression levels observed in groups A, B, and C. significantly altered levels of inflammatory factors in the samples of keloid patients were observed, indicating that the formation of keloids potentially associated with the inflammatory response. HBO therapy can significantly affect expression levels of IL-12p40, MIP-1β, PDGF-BB, and IL-1Ra, suggesting that the effects of HBO therapy is associated with attenuation of the inflammatory response.
Effects of hyperbaric oxygen therapy on the expression levels of the inflammatory factors interleukin-12p40, macrophage inflammatory protein-1β, platelet-derived growth factor-BB, and interleukin-1 receptor antagonist in keloids.
Giardia lamblia p65RelA Reducing NF-kB proteins and modulate the level of LPS-induced pro-inflammatory response in macrophages.
Protozoan Giardia lamblia is the most common cause of gastrointestinal parasitic infections worldwide. parasites developed sophisticated, yet not fully disclosed, mechanisms to escape the immune system and the growth in the intestine. To better understand the interaction of G. lamblia by host immune cells, we examined the ability of the parasite to modulate canonical activation of mouse macrophages (Raw 264.7 cell line) and human monocyte-derived macrophages induced by TLR4 agonist, lipopolysaccharide (LPS). We observed that LPS-destructive G.
Description: Recombinant MIP-1 alpha is a disulfide-linked homodimeric protein consisting of 70 amino acid residues, and migrates as an approximately 8 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human MIP-1 alpha chain was expressed in E. coli.
Description: Recombinant MIP-1 alpha is a disulfide-linked homodimeric protein consisting of 70 amino acid residues, and migrates as an approximately 8 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human MIP-1 alpha chain was expressed in E. coli.
MIP-1a Macrophage Inflammatory Protein-1 Alpha Mouse Recombinant Protein (CCL3)
Description: Macrophage Inflammatory Protein-1 alpha Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 69 amino acids and having a molecular mass of 7820 Dalton. ;The MIP-1a is purified by proprietary chromatographic techniques.
Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody
Description: Macrophage Inflammatory Protein-1 alpha His Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 68 amino acids and having a molecular mass of 7820 Dalton with an amino-terminal hexahistidine tag. ;The MIP-1a-His is purified by proprietary chromatographic techniques.
Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody
Description: MIP-3 Alpha Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 8 kDa. ;The MIP-3a is purified by proprietary chromatographic techniques.
BSA Conjugated Macrophage Inflammatory Protein 1 Alpha (MIP1a)
Description: Recombinant Human Active Macrophage Inflammatory Protein 3 Alpha (MIP3a) expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells
Active Macrophage Inflammatory Protein 3 Alpha (MIP3a)
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Bovine Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Canine Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Canine Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from serum, plasma or other biological fluids.
Canine Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Canine Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from serum, plasma or other biological fluids.
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Rat Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Rat Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Rat Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Rat Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Macrophage Inflammatory Protein 1 Alpha (MIP1a) Monoclonal Antibody (Human)
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a)CLIA Kit
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a)CLIA Kit
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a)CLIA Kit
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) CLIA Kit
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Macrophage Inflammatory Protein 1 Alpha (MIP1a)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids
Dog Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Dog Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma and other biological fluids.
Dog Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Dog Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma and other biological fluids.
Dog Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Dog Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma and other biological fluids.
Dog Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Dog Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma and other biological fluids.
Dog Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Dog Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from Serum, plasma and other biological fluids. with no significant corss-reactivity with analogues from other species.
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.
Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) in samples from Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.
Rat Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Macrophage Inflammatory Protein 1 Alpha (MIP1a) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
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lamblia generate pro-inflammatory status in these macrophage-like cells through inhibition of cyclooxygenase-2 and inducible nitric oxide synthase expression and NO production next. This effect is partly due to the activity of three protease G. lamblia, 135 kDa cysteine protease metalloprotease and two with 75 and 63 kDa, which divides the p65RelA subunit of nuclear factor-kappa B (NF-kB). In addition, TNF and CCl4 transcription increases with the presence of parasites. Overall, our data suggest that the G. lamblia modulated macrophage inflammatory response through a reduction in the value of NF-kB, thus silencing the critical signaling pathways of innate host immune response.
Pneumonia is the leading cause of hospitalization worldwide. In addition to viral, bacterial co-infection dramatically worsen the infection. In general, the surfactant protein A (SP-A) is the first line of immune defense. In this study, we analyzed whether influenza A virus (IAV) and / or Staphylococcus aureus (S. aureus) infection affects the expression of SP-A. To reflect the situation in the lungs, we used a model of human alveolar-on-a-chip and murine model of pneumonia.
